Oligonucleotide Synthesis, RNA Raw Materials & Modification

8-Hydroxy-2'-deoxyguanosine

Oligonucleotide Synthesis, RNA Raw Materials & Modification

製品番号CH64071CAS番号88847-89-6純度>=98%

製品画像はありません

製品概要

クイックビュー

製品ファミリー: Oligonucleotide Synthesis, RNA Raw Materials & Modification
分子式: C10H13N5O5
分子量: 283.24
純度: >=98%

8-Hydroxy-2'-deoxyguanosine (8-oxo-dG) is the C8-oxidized form of 2'-deoxyguanosine. CH64071 is identified by CAS 88847-89-6, molecular formula C10H13N5O5, molecular weight 283.24, PubChem CID 135440064, and InChIKey HCAJQHYUCKICQH-VPENINKCSA-N.

The cited oxidative-stress literature discusses 8-hydroxy-2'-deoxyguanosine as a form of oxidative DNA damage and a marker of cellular oxidative stress. CH64071 provides the 8-oxo-dG identity for oxidative DNA damage, oxidized nucleoside, and nucleoside chemistry research.

別名

8-Hydroxy-2'-deoxyguanosine; 8-oxo-dG; 8-oxo-2'-deoxyguanosine; 8-OHdG

同定情報と仕様

Catalog No.	CH64071
CAS No.	88847-89-6
Molecular Formula	C10H13N5O5
Molecular Weight	283.24
PubChem CID	135440064
InChIKey	HCAJQHYUCKICQH-VPENINKCSA-N
Purity	>=98%

保管条件

-20 C

技術属性

Nucleobase: Oxidized guanine
Sugar: 2'-Deoxyribose
Base modification: 8-Hydroxy / 8-oxo
Research role: Oxidative-DNA-damage nucleoside reference
Grade: for Biochemistry
Packaging: 5 mg; 5 umol (~1.5 mg); 5 x 5 umol; Custom packaging on request
Physical form: crystalline solid
Stability: >=4 years

用途情報

Oxidative-DNA-damage marker research: the cited literature discusses 8-oxo-dG as a form of oxidative DNA damage and a marker of cellular oxidative stress.
Oxidized nucleoside reference: CH64071 provides the 8-hydroxy-2'-deoxyguanosine identity for oxidized nucleoside and nucleoside chemistry research.

公開情報源

Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
PubChem化合物 135440064
PubChem · CID 135440064

よくある質問

How does it differ from 2'-deoxyguanosine?

It is the C8-oxidized (8-oxo/8-hydroxy) form of 2'-deoxyguanosine, whereas 2'-deoxyguanosine is unmodified. 2'-deoxyguanosine is cataloged separately.