Oligonucleotide Synthesis, RNA Raw Materials & Modification

N6-Methyl-2'-deoxyadenosine

Oligonucleotide Synthesis, RNA Raw Materials & Modification

製品番号CH64079CAS番号2002-35-9純度>=99.0% (HPLC)

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製品概要

クイックビュー

製品ファミリー: Oligonucleotide Synthesis, RNA Raw Materials & Modification
分子式: C11H15N5O3
分子量: 265.27
純度: >=99.0% (HPLC)

N6-Methyl-2'-deoxyadenosine is 2'-deoxyadenosine methylated at the adenine N6 position, corresponding to the nucleoside form of DNA N6-methyladenine (6mA). CH64079 is identified by CAS 2002-35-9, molecular formula C11H15N5O3, molecular weight 265.27, PubChem CID 168948, and InChIKey DYSDOYRQWBDGQQ-XLPZGREQSA-N.

The cited literature discusses DNA N6-methyladenine (6mA) as an adenine-methylation epigenetic modification. Unlike acyl-protected building blocks, the N6-methyl group is a permanent base modification, not a removable protecting group.

別名

N6-Methyl-2'-deoxyadenosine; N6-Me-dA; 6mA nucleoside; N6-methyl-dA

同定情報と仕様

Catalog No.	CH64079
CAS No.	2002-35-9
Molecular Formula	C11H15N5O3
Molecular Weight	265.27
PubChem CID	168948
InChIKey	DYSDOYRQWBDGQQ-XLPZGREQSA-N
Purity	>=99.0% (HPLC)

保管条件

-20 C

技術属性

Nucleobase: Adenine
Sugar: 2'-Deoxyribose
Base modification: N6-Methyl (6mA)
Research role: DNA epigenetic-mark nucleoside reference
Packaging: 25 mg; 100 mg; Custom packaging on request
Water content: <=5.0% KF
Physical form: white powder
Stability: >=4 years

用途情報

6mA epigenetic-mark research: CH64079 is the nucleoside form of DNA N6-methyladenine (6mA), an adenine-methylation epigenetic modification discussed in the cited literature.
Base-modified nucleoside reference: CH64079 provides the N6-methyl-2'-deoxyadenosine identity for nucleoside chemistry research.

公開情報源

Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
PubChem化合物 168948
PubChem · CID 168948

よくある質問

Is the N6-methyl group a protecting group?

No. Unlike the N6-acyl (benzoyl/acetyl) building blocks, the N6-methyl here is a permanent base modification — the nucleoside form of the DNA epigenetic mark N6-methyladenine (6mA) — not a group that is removed during deprotection.

What is 6mA?

6mA (N6-methyladenine) is an adenine-methylation epigenetic modification in DNA. CH64079 is the corresponding N6-methyl-2'-deoxyadenosine nucleoside identity.