CHEMOS
Oligonucleotide Synthesis, RNA Raw Materials & Modification

N2-Isobutyrylguanosine

Oligonucleotide Synthesis, RNA Raw Materials & Modification

製品番号CH64083CAS番号64350-24-9純度95%
製品画像はありません

製品概要

クイックビュー

製品ファミリー
Oligonucleotide Synthesis, RNA Raw Materials & Modification
分子式
C14H19N5O6
分子量
353.33
純度
95%

N2-Isobutyrylguanosine (rGiBu) is guanosine whose guanine exocyclic N2-amine is protected with an isobutyryl group. CH64083 is identified by CAS 64350-24-9, molecular formula C14H19N5O6, molecular weight 353.33, PubChem CID 135722152, and InChIKey OXTYJSXVUGJSGM-HTVVRFAVSA-N.

The cited oligonucleotide-synthesis literature discusses exocyclic-amine protecting groups on nucleobases and their removal during deprotection. CH64083 provides the N2-isobutyryl-protected guanosine identity for RNA building-block and nucleoside chemistry research.

別名

N2-Isobutyrylguanosine; N2-ibu-rG; rGiBu

同定情報と仕様

Catalog No.CH64083
CAS No.64350-24-9
Molecular FormulaC14H19N5O6
Molecular Weight353.33
PubChem CID135722152
InChIKeyOXTYJSXVUGJSGM-HTVVRFAVSA-N
Purity95%

保管条件

Refrigerator

技術属性

Nucleobase
Guanine
Sugar
D-Ribose
Base protection
N2-Isobutyryl
Synthesis role
Base-protected RNA nucleoside intermediate
Packaging
1 g; 5 g; 10 g; Custom packaging on request
Physical form
crystal-powder; white to almost white

用途情報

  • Base-protected RNA building block: the N2-isobutyryl group masks the guanine exocyclic amine in RNA oligonucleotide-synthesis chemistry and is removed during deprotection.
  • Guanosine (rG) monomer precursor context: CH64083 is the base-protected guanosine identity relevant to guanine building-block preparation.
  • Nucleoside chemistry reference: CH64083 provides the N2-isobutyrylguanosine (rGiBu) identity for nucleoside chemistry research.

関連技術資料

オリゴヌクレオチド修飾

ASO、siRNA、guide RNA、aptamer、研究用オリゴの糖、塩基、骨格、末端、コンジュゲーション修飾。

オリゴヌクレオチド合成

修飾モノマー、担体、硫化試薬、キャップ 類似体、関連するオリゴ合成入力物の支援。

公開情報源

よくある質問

Why is the N2-amine of this guanosine protected with isobutyryl?

In RNA oligonucleotide synthesis the reactive exocyclic amine of guanine is masked with a protecting group such as isobutyryl to prevent side reactions; the isobutyryl group is later removed during deprotection.

How does it differ from N2-isobutyryl-2'-deoxyguanosine?

Both carry an N2-isobutyryl-protected guanine, but this one is the ribonucleoside (2'-OH), while N2-isobutyryl-2'-deoxyguanosine is the 2'-deoxy form. Both are cataloged separately.

類似製品

2',3',5'-Tri-O-acetyl-D-adenosine

CAS番号
7387-57-7
分子式
C16H19N5O7
分子量
393.35

L-Threoninol

CAS番号
3228-51-1
分子式
C4H11NO2
分子量
105.14

Tetrabenzyl pyrophosphate

CAS番号
990-91-0
分子式
C28H28O7P2
分子量
538.47

2'-Deoxyadenosine Monohydrate

CAS番号
16373-93-6
分子式
C10H15N5O4
分子量
269.26

材料選択の支援が必要ですか？

CHEMOSは製品適合性、目標構造、ルート上の課題、分析要件、プロジェクト別供給ニーズを確認します。

プロジェクト支援を見る