CHEMOS
Oligonucleotide Synthesis, RNA Raw Materials & Modification

N6-Benzoyl-2'-O-methyladenosine

Oligonucleotide Synthesis, RNA Raw Materials & Modification

製品番号CH64086CAS番号85079-00-1純度>=98.0% (HPLC)
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製品概要

クイックビュー

製品ファミリー
Oligonucleotide Synthesis, RNA Raw Materials & Modification
分子式
C18H19N5O5
分子量
385.37
純度
>=98.0% (HPLC)

N6-Benzoyl-2'-O-methyladenosine is 2'-O-methyladenosine whose adenine exocyclic N6-amine is protected with a benzoyl group. CH64086 is identified by CAS 85079-00-1, molecular formula C18H19N5O5, molecular weight 385.37, PubChem CID 13852840, and InChIKey PHFHSPQCDRKMQJ-XWXWGSFUSA-N.

The cited oligonucleotide-synthesis literature discusses exocyclic-amine protecting groups and their removal during deprotection. In the cited 2'-O-methyl literature, 2'-O-methyl ribonucleosides/residues are discussed for nuclease resistance and RNA affinity.

別名

N6-Benzoyl-2'-O-methyladenosine; N6-Bz-2'-OMe-rA; 2'-OMe-rA(Bz)

同定情報と仕様

Catalog No.CH64086
CAS No.85079-00-1
Molecular FormulaC18H19N5O5
Molecular Weight385.37
PubChem CID13852840
InChIKeyPHFHSPQCDRKMQJ-XWXWGSFUSA-N
Purity>=98.0% (HPLC)

保管条件

2-8 C; keep dark and dry

技術属性

Nucleobase
Adenine
Sugar modification
2'-O-Methyl
Base protection
N6-Benzoyl
Synthesis role
Base-protected 2'-O-methyl nucleoside intermediate
Packaging
1 g; 5 g; Custom packaging on request
Water content
<=6.0%
Physical form
white powder

用途情報

  • Base-protected 2'-OMe building block: the N6-benzoyl group masks the adenine exocyclic amine in oligonucleotide-synthesis chemistry and is removed during deprotection.
  • 2'-OMe sugar modification context: cited 2'-O-methyl literature discusses 2'-OMe residues for nuclease resistance and RNA affinity.
  • Nucleoside chemistry reference: CH64086 provides the N6-benzoyl-2'-O-methyladenosine identity for nucleoside chemistry research.

関連技術資料

オリゴヌクレオチド修飾

ASO、siRNA、guide RNA、aptamer、研究用オリゴの糖、塩基、骨格、末端、コンジュゲーション修飾。

オリゴヌクレオチド合成

修飾モノマー、担体、硫化試薬、キャップ 類似体、関連するオリゴ合成入力物の支援。

公開情報源

よくある質問

How does it differ from N6-benzoyladenosine?

Both carry an N6-benzoyl-protected adenine, but this one also has a 2'-O-methyl sugar modification, whereas N6-benzoyladenosine has a free 2'-OH. N6-benzoyladenosine is cataloged separately.

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