Lipig
Oligonucleotide Conjugation & Delivery Ligands
製品概要
クイックビュー
- 製品ファミリー
- Oligonucleotide Conjugation & Delivery Ligands
- 分子式
- C78H125N7O42
- 分子量
- 1832.8
- 純度
- >98%
Lipig is a PubChem-verified acetyl-protected N-acetyl-sugar glycoconjugate building block catalogued in the CHEMOS GalNAc/conjugate line. Key identifiers include CAS 1332358-27-6, molecular formula C78H125N7O42, molecular weight 1832.8, InChIKey RNUIVLALNYHRTI-OIZVDVEISA-N, and PubChem CID 58409185.
Lipig is presented for oligonucleotide conjugation / GalNAc-type delivery-ligand building-block context. GalNAc-ASGPR binding is included only as molecular-recognition background for the ligand class, while CH67006 remains a catalog building-block identity.
別名
Lipig; acetyl-protected N-acetyl-sugar glycoconjugate; GalNAc-type glycoconjugate building block
同定情報と仕様
| Catalog No. | CH67006 |
| CAS No. | 1332358-27-6 |
| Molecular Formula | C78H125N7O42 |
| Molecular Weight | 1832.8 |
| PubChem CID | 58409185 |
| InChIKey | RNUIVLALNYHRTI-OIZVDVEISA-N |
| Purity | >98% |
保管条件
-20 +/- 5 C
技術属性
- Material class
- Acetyl-protected N-acetyl-sugar glycoconjugate
- Structural family
- GalNAc-type glycoconjugate
- Protection state
- Acetyl-protected
- Packaging
- Custom packaging on request
用途情報
- Glycoconjugate building block: a PubChem-verified acetyl-protected N-acetyl-sugar conjugate for oligonucleotide conjugation / GalNAc-type delivery-ligand chemistry.
- Building-block scope: use the record for identity matching and conjugation-context inquiries for the listed building block.
- GalNAc class context: GalNAc ligands bind the asialoglycoprotein receptor (ASGPR), cited here only as molecular-recognition background.
関連技術資料
公開情報源
- Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency in mice
Nucleic Acids Research, 2014
Product-family technical context
- Multivalent N-acetylgalactosamine-conjugated siRNA localizes in hepatocytes and elicits RNAi-mediated gene silencing
Journal of the American Chemical Society, 2014
Product-family technical context
- siRNA Conjugates Carrying Sequentially Assembled Trivalent N-Acetylgalactosamine Linked Through Nucleosides Elicit Robust Gene Silencing In Vivo in Hepatocytes
ACS Chemical Biology, 2015
Product-family technical context
- Comparative Characterization of Hepatic Distribution and mRNA Reduction of Antisense Oligonucleotides Conjugated with Triantennary N-Acetyl Galactosamine and Lipophilic Ligands
Journal of Pharmacology and Experimental Therapeutics, 2016
Product-family technical context
- PubChem化合物 58409185
PubChem · CID 58409185
よくある質問
What is Lipig?
It is a PubChem-verified acetyl-protected N-acetyl-sugar glycoconjugate building block (CAS 1332358-27-6, C78H125N7O42) catalogued in the CHEMOS GalNAc/conjugate line.
How should the GalNAc-ASGPR context be read?
GalNAc-ASGPR binding is molecular-recognition background for the ligand class. CH67006 is presented here as a catalog building-block identity.
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