UDP-GalNAz.2Na
disodium;[(2R,3R,4R,5R,6R)-3-[(2-azidoacetyl)amino]-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl] [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] phosphate
製品概要
クイックビュー
- 製品ファミリー
- Click Chemistry & Bioconjugation Reagents
- 化学名
- disodium;[(2R,3R,4R,5R,6R)-3-[(2-azidoacetyl)amino]-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl] [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] phosphate
- 分子式
- C17H24N6Na2O17P2
- 分子量
- 692.3
- 純度
- 99.89%
UDP-GalNAz.2Na is a disodium UDP-N-azidoacetylgalactosamine nucleotide-sugar donor for glycosyltransferase and chemoenzymatic labeling research. PubChem records the exact source name and UDP-GalNAz disodium name as CID 166638300, CAS 653600-61-4, molecular formula C17H24N6Na2O17P2, molecular weight 692.3, exact mass 692.04685588, and InChIKey XGTPLFSPWJKVQB-SGNQCPJASA-L.
The UDP-sugar scaffold supports enzymatic transfer workflows, while the azido GalNAc handle enables downstream bioorthogonal tagging with compatible click probes in analytical glycoproteomics or glycomics studies.
別名
UDP-GalNAz disodium; UDP-GalNAz.2Na; UDP-Azido-GalNAc disodium; uridine 5'-diphospho-N-azidoacetylgalactosamine disodium salt
同定情報と仕様
| Catalog No. | CH70481 |
| Product Name | UDP-GalNAz.2Na |
| CAS No. | 653600-61-4 |
| PubChem CID | 166638300 |
| Molecular Formula | C17H24N6Na2O17P2 |
| Molecular Weight | 692.3 |
| Exact Mass | 692.04685588 |
| InChIKey | XGTPLFSPWJKVQB-SGNQCPJASA-L |
| Synonyms | UDP-GalNAz disodium; UDP-Azido-GalNAc disodium |
| Purity | 99.89% |
保管条件
Powder: -20 C or 4 C; in solvent: -80 C or -20 C; sealed and protected; avoid moisture
技術属性
- Nucleotide-sugar class
- UDP-GalNAc analog
- N-acyl modification
- N-Azidoacetyl
- Bioorthogonal handle
- Azide
- Counterion form
- Disodium salt
- Packaging
- 1 mg; 5 mg; 10 mg; Custom packaging on request
- Physical form
- Powder
- Stability
- Powder: 3 years at -20 C or 2 years at 4 C; in solvent: 6 months at -80 C or 1 month at -20 C
用途情報
- Glycosyltransferase research: UDP-GalNAz.2Na is a nucleotide-sugar donor for workflows studying GalNAc-transferase and related glycosylation systems.
- Chemoenzymatic labeling: the azido GalNAc group supports enzymatic labeling workflows followed by click-compatible probe tagging.
- Analytical glycoproteomics: UDP-GalNAz.2Na is relevant to workflows combining enzymatic labeling, bioorthogonal tagging, and mass-spectrometry analysis.
補足材料情報
用途
Use in research workflows that require an azido GalNAc UDP-sugar donor for glycosyltransferase studies, chemoenzymatic labeling, or analytical glycoproteomics method development.
特性
UDP-GalNAz.2Na combines a UDP nucleotide-sugar donor scaffold with an azidoacetyl GalNAc analog. This design supports enzymatic transfer workflows and leaves an azide handle for downstream bioorthogonal tagging.
関連技術資料
公開情報源
- A strain-promoted [3 + 2] azide-alkyne cycloaddition for covalent modification of biomolecules in living systems
Journal of the American Chemical Society, 2004
Product-family technical context
- Copper-free click chemistry for dynamic in vivo imaging
Proceedings of the National Academy of Sciences, 2007
Product-family technical context
- A Strain-Promoted [3 + 2] Azide–Alkyne Cycloaddition for Covalent Modification of Biomolecules in Living Systems
Journal of the American Chemical Society, 2004
Product-family technical context
- Tetrazine Ligation: Fast Bioconjugation Based on Inverse-Electron-Demand Diels–Alder Reactivity
Journal of the American Chemical Society, 2008
Product-family technical context
- PubChem化合物 166638300
PubChem · CID 166638300
よくある質問
What is UDP-GalNAz.2Na?
UDP-GalNAz.2Na is the disodium form of UDP-N-azidoacetylgalactosamine, an azido GalNAc nucleotide-sugar donor. PubChem records it as CID 166638300 with CAS 653600-61-4.
How is UDP-GalNAz.2Na used in research workflows?
It is used as a UDP-sugar donor in glycosyltransferase and chemoenzymatic labeling workflows. The azido GalNAc group can support downstream click-compatible probe tagging.
Is UDP-GalNAz.2Na the same as Ac4GalNAz?
No. UDP-GalNAz.2Na is a nucleotide-sugar donor for enzymatic transfer workflows, while Ac4GalNAz is a protected metabolic sugar precursor. They should not be described interchangeably.
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