Azido-mono-amide-DOTA
화학명
2-[4-[2-(3-azidopropylamino)-2-oxoethyl]-7,10-bis(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetic acid
Azido-mono-amide-DOTA•DOTA
Structure: 
제품 번호
CH54007
CAS
1227407-76-2
분자식
C19H34N8O7
분자량
486.53
사양
| Catalog No. | CH54007 |
| CAS No. | 1227407-76-2 |
| Molecular Formula | C19H34N8O7 |
| Molecular Weight | 486.53 |
CHEMOS Support for This Category
CHEMOS supports DOTA chelator and radiopharmaceutical building-block chemistry, including protected, activated, PEG-spaced, and conjugation-ready intermediates. DOTA and DOTA-GA derivatives : protected chelators, activated esters, maleimide derivatives, and linker-spaced variants. Custom chelator-linker synthesis : route design for chelator-linker-targeting moiety intermediates. Metal-sensitive process control : purification and analytical planning for low-metal-background requirements. Analytical support : HPLC, NMR, MS, and ICP-MS can be discussed according to project needs. Scale-up support : process optimization and batch-size planning after technical review.
개요
Azido-mono-amide-DOTA (also known as 2-[4-[2-(3-azidopropylamino)-2-oxoethyl]-7,10-bis(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetic acid) (CAS 1227407-76-2, MF C19H34N8O7, MW 486.53) is part of the DOTA chelator family used in targeted radioligand and imaging-conjugate research. Practical chemistry topics include mono-functionalisation of the macrocycle, protection-group strategy, and conjugation chemistry with peptides or antibodies. Project scale-up and custom synthesis are coordinated by the CHEMOS R&D team across laboratory and production sites.
응용
- Azido-mono-amide-DOTA (1227407-76-2) supply and analog preparation for research programs
- Antibody and peptide radiolabeling research
- Custom synthesis of mono-functionalised DOTA derivatives
- Trace-metal control studies for radiopharmaceutical conjugates