Azido-PEG4-alcohol

Azido-PEG4-alcohol

화학명

2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethanol

Azido-PEG4-alcoholPROTAC
Structure: Azido-PEG4-alcohol structure, CAS 86770-67-4, MW 219.24
제품 번호
CH56006
CAS
86770-67-4
분자식
C8H17N3O4
분자량
219.24
사양
Catalog No.CH56006
CAS No.86770-67-4
Molecular FormulaC8H17N3O4
Molecular Weight219.24

CHEMOS Support for This Category

CHEMOS supports PROTAC building-block projects covering linkers, E3 ligase recruiter derivatives, and customized degrader intermediates. Linker building blocks : PEG acids, PEG azides, alkyl spacers, branched linkers, and rigid linkers. E3 recruiter derivatives : IMiD-related, VHL-related, and other recruiter building blocks for medicinal chemistry programs. Custom synthesis : linker design, functional-group installation, and intermediate preparation. Route and purification review : multi-step synthesis planning with attention to polarity, solubility, and impurity control. Scale-up evaluation : larger-batch preparation can be assessed after route feasibility review.

개요

Azido-PEG4-alcohol (also known as 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethanol) (CAS 86770-67-4, MF C8H17N3O4, MW 219.24) is a PROTAC research building block — typically a linker, E3-ligase ligand, or degrader handle. Practical chemistry topics include orthogonal protecting groups, modular linker chemistry, and stereo-purity at chiral centres. CHEMOS process chemistry, organic synthesis routes and project scale-up support are offered for downstream programs.

응용

  • Azido-PEG4-alcohol (CAS 86770-67-4) route review and custom analog preparation
  • PROTAC building block — linker / E3-ligand / degrader handle
  • Linker-length and composition exploration for degrader optimisation
  • Process-development support for scalable building-block preparation

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