EN171
화학명
1-(7-benzyl-2,7-diazaspiro[4.4]nonan-2-yl)prop-2-en-1-one
EN171•Molecular Glues
Structure: 
제품 번호
CH57013
CAS
2191110-79-7
분자식
C17H22N2O
분자량
270.37
사양
| Catalog No. | CH57013 |
| CAS No. | 2191110-79-7 |
| Molecular Formula | C17H22N2O |
| Molecular Weight | 270.37 |
CHEMOS Support for This Category
CHEMOS supports molecular glue and small-molecule degrader building-block chemistry, including analog preparation and route optimization. Scaffold preparation : IMiD-related analogs, sulfonamide motifs, and other functionalized small-molecule scaffolds. Custom analog synthesis : substituent variation, linker-ready handles, and SAR-oriented intermediate preparation. Chiral and stereochemical review : chiral separation or asymmetric synthesis can be evaluated where relevant. Analytical support : HPLC, NMR, MS, and purity-method development according to project needs. Process development : route refinement and scale-up planning after technical review.
개요
EN171 (also known as 1-(7-benzyl-2,7-diazaspiro[4.4]nonan-2-yl)prop-2-en-1-one) (CAS 2191110-79-7, MF C17H22N2O, MW 270.37) is a small-molecule scaffold studied in targeted protein degradation research, with potential relevance to molecular glue or E3-ligase modulation chemistry. Practical chemistry topics include enantioselective synthesis, scaffold modification, and related-substance profiling. CHEMOS process chemistry, organic synthesis routes and project scale-up support are offered for downstream programs.
응용
- EN171 (CAS 2191110-79-7) route review and custom analog preparation
- Custom synthesis of analog series for SAR exploration
- Reference research scaffold in degrader chemistry programs
- Analog screening for E3-ligase recruitment chemistry